Monitoring of Anti-tuberculosis Therapy

·         For each patient with newly diagnosed TB disease, a specific treatment and monitoring plan should be developed in collaboration with the local TB control program within 1 week of the presumptive diagnosis.

·         This plan should include:
o    Description of the TB treatment regimen
o    Methods of assessing and ensuring adherence to the TB treatment regimen;
o    Methods to monitor for adverse reactions; and
o    Methods for evaluating treatment response.

·         A number of measures are monitored to determine response to treatment.
·         These can broadly be divided into clinical and microbiological markers.
·         Physical signs of tuberculosis treatment success include:
o    A reduction in symptoms, such as less coughing
o    Overall improvement in the way one feels
o    Weight gain
o    Increased appetite
o    Improvement in strength and stamina
·         Laboratory Tests to Monitor Tuberculosis Treatment
  • Lab tests including Sputum tests are performed during tuberculosis treatment to determine if any TB bacteria are left in the TB patient.
References

Wells BG, DiPiro J, Schwinghammer T (2013), Pharmacotherapy Handbook (6th Ed). New York, NY: McGraw-Hill.

DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey ML, (2008): Pharmacotherapy: A Pathophysiologic Approach (7th ed): New York, NY: McGraw-Hill.

Katz M D., Matthias KR., Chisholm-Burns M A., Pharmacotherapy(2011) Principles & Practice Study Guide: A Case-Based Care Plan Approach: New York, NY: McGraw-Hill.

Schwinghammer TL, Koehler JM (2009) Pharmacotherapy Casebook: A Patient-Focused Approach (7th ed): New York, NY: McGraw-Hill.

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